ESTRADIOL - (First line)

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Patches (Evorel®) 25, 50, 75, 100 micrograms/24 hours

Dosage:

1 patch to be applied twice weekly continuously. Initiate therapy with 50 microgram patch for first month, subsequently adjusted to lowest effective dose.

Important: Formulation and dosage details

Formulation:

Patches (Estraderm MX®) 25, 50, 75, 100 micrograms/24 hours

Dosage:

1 patch to be applied twice weekly continuously. Initiate therapy with the 25 microgram patch for first 3 months, subsequently adjusted to lowest effective dose.

Important: Formulation and dosage details

Formulation:

Patches (Estradot®) 25, 37·5, 50, 75, 100 micrograms/24 hours (s) 

Dosage:

For patients undergoing gender reassignment off-label, 1 patch to be applied twice weekly continuously.

Important: Formulation and dosage details

Formulation:

Gel (Oestrogel® Pump-Pack 0·06%) 750 microgram/actuation

Dosage:

Apply 1·5mg once daily continuously, increased if necessary up to 3 mg after 1 month continuously, to be applied over a large area, to be used with cyclical progestogen for at least 12 days of each cycle in women with a uterus. If switching from cyclical HRT, start at end of regimen; otherwise start at any time.

Editorial Information

Document Id: F339