Hormone Replacement Therapy (HRT)
Refer to Menopause and HRT guidance for further information, also note NICE guidance NG23 Menopause: diagnosis and management. Oral preparations are usually first-line unless not tolerated. Where patients have persistent oestrogenic side-effects, reduce dose and change preparation or move to a transdermal preparation. For patients with risk factors for venous thromboembolism or stroke consider transdermal preparations.
MHRA advice: Hormone replacement therapy (HRT): further information on the known increased risk of breast cancer with HRT and its persistence after stopping (August 2019) (www.gov.uk).
For information on HRT supply shortages see medicines shortage log (intranet access required) and shortages information.