Gonadorelin analogues (Formulary)

For the use of gonadorelin analogues in

  • prostate cancer see here
  • breast cancer see here 

TRIPTORELIN - (First line)

Important: Therapy notes

  • The treatment of children with Decapeptyl SR 11·25mg or 22·5mg should be under the overall supervision of a paediatric endocrinologist or of a paediatrician or an endocrinologist with expertise in the treatment of central precocious puberty.
  • The vial includes an overage to allow administration of the dose.

Important: Formulation and dosage details

Formulation:

Powder for suspension for injection vial (Decapeptyl® SR) 3mg, 11·25mg, 22·5mg (s)

Dosage:

Endometriosis and reduction in size of uterine fibroids, by intramuscular injection, 3mg every 4 weeks starting during first 5 days of menstrual cycle; for uterine fibroids continue treatment for at least 3 months; maximum duration of treatment 6 months (not to be repeated);

Endometriosis, by intramuscular injection, 11·25mg every 3 months for maximum 6 months (not to be repeated) starting during first 5 days of menstrual cycle.

GOSERELIN

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Implant, pre-filled disposable injection 3·6mg (specialist use only)

Dosage:

Endometriosis, by subcutaneous injection, 3·6mg every 28 days, maximum duration of treatment 6 months (do not repeat).

Before surgery in women who have anaemia due to uterine fibroids, 3·6mg every 28 days, maximum duration of treatment 3 months.

Editorial Information

Document Id: F193