Warning

MAVACAMTEN

Important: Therapy notes

  • Bioequivalence between different capsule strengths has not been confirmed, therefore only one capsule of the appropriate strength should be used to achieve the prescribed dose and not multiple capsules. See: mavacamten.
  • A patient card and patient guide should be provided: Camzyos 15mg hard capsules - Risk Management Materials.

Important: Formulation and dosage details

Formulation:

Capsules 2.5mg, 5mg, 10mg, 15mg (Restricted: Hospital use only)

Dosage:

As per SMC2618: for the treatment of symptomatic (New York Heart Association, NYHA, class II to III) obstructive hypertrophic cardiomyopathy (oHCM) in adult patients.

Responsibilities

Specialist team:

  • Pre-treatment screening, as per BNF
  • Monitoring requirements, as per BNF
  • Clinical review and planned treatment cessation

Primary care team (when the medicine becomes available): 

  • Maintenance prescribing under the direction of the specialist team

Editorial Information

Last reviewed: 31/10/2024

Next review date: 30/11/2025

Document Id: F393