Important: Therapy notes
- Bioequivalence between different capsule strengths has not been confirmed, therefore only one capsule of the appropriate strength should be used to achieve the prescribed dose and not multiple capsules. See: mavacamten.
- A patient card and patient guide should be provided: Camzyos 15mg hard capsules - Risk Management Materials.
Important: Formulation and dosage details
Formulation:
Capsules 2.5mg, 5mg, 10mg, 15mg (Restricted: Hospital use only)
Dosage:
As per SMC2618: for the treatment of symptomatic (New York Heart Association, NYHA, class II to III) obstructive hypertrophic cardiomyopathy (oHCM) in adult patients.
Responsibilities
Specialist team:
- Pre-treatment screening, as per BNF
- Monitoring requirements, as per BNF
- Clinical review and planned treatment cessation
Primary care team (when the medicine becomes available):
- Maintenance prescribing under the direction of the specialist team