Around one third of patients suffering from carpel tunnel syndrome who are treated with wrist splints at night get better without any other treatment. This means that treatment with injections or surgery may be avoided by using a splint on your wrist at night.
Wrist splints are safe. The purpose of the splint is to stop the nerve being compressed at night when you are asleep.
Fitting
The splint should be a comfortable fit, tight enough to hold your wrist in position, but so tight as to affect your circulation or make your wrist swell. The rough side of the Velcro should not touch your skin, so if it does you will need a bigger size.
If the metal strut on the palm side digs into your palm, then you can straighten it out slightly. If your hands are not strong you might need help with this.