Where an NSAID is indicated, the lowest effective dose should be used for the shortest possible duration to control symptoms.
The choice of NSAID depends on patient characteristics, medical history, and the type of complaint.
All NSAIDs have been associated with serious GI toxicity, a small increased risk of thrombotic events and rarely precipitating renal failure. The appropriateness of NSAID prescribing should be reviewed on a routine basis, particularly in those at higher risk of GI, renal and cardiovascular morbidity and mortality.
The NICE CKS: NSAIDs – Prescribing Issues provides further information on factors that should be considered when prescribing NSAIDs.