NICE clinical guideline CG184 provides information on the investigation and management of gastro-oesophageal reflux disease (GORD) and dyspepsia in adults.
In most patients with GORD, adequate symptom control is the principal aim of treatment. Symptoms should be controlled by using the lowest dose of the most cost–effective agent (antacid, H2 receptor antagonist or proton pump inhibitor). An ‘on demand’ regimen is acceptable providing it is effective.