Lumbar puncture contraindicated
Commence empiric antibiotics for suspected meningitis without delay:
Children under 3 months:
- IV cefotaxime and either amoxicillin or ampicillin (can replace cefotaxime with ceftriaxone if no contraindication)
- Add vancomycin if recently overseas or prolonged or multiple antibiotic exposure within the last three months.
Children 3 months and over:
- IV ceftriaxone unless contraindicated
- Add vancomycin if recently overseas or prolonged or multiple antibiotic exposure within the last three months.
Contraindications to ceftriaxone: premature neonates with corrected gestational age under 41 weeks and other neonates under 1 month old, particularly those with jaundice, hypoalbuminemia, or acidosis; or receiving concomitant treatment with intravenous calcium.