Why the committee made the recommendation
Evidence for children aged 5 to 11 showed that regular paediatric low-dose ICS plus SABA as needed was superior to SABA alone, particularly in reducing exacerbations. Using regular ICS did not cause more side effects and was not associated with greater adrenal suppression. There was no evidence for ICS/formoterol combination inhalers used as needed in this age group. The committee therefore recommended regular paediatric low-dose ICS as the preferred treatment option for children aged 5 to 11. However, in view of the evidence supporting the use of ICS/LABA as needed combination inhalers in adults, they made a research recommendation to test the benefits of this combination in children.
How the recommendation might affect practice
The recommendation for treatment of newly diagnosed asthma in children is in line with current practice.
Full details of the evidence and the committee’s discussion are in evidence review P: drug classes for initial asthma management.