- Blood cultures: 3 sets (10ml per bottle), spaced 30mins apart, from 3 different sites.
- Obtain cardiology opinion.
Endocarditis
Antibiotics should not be started unless the patient has sepsis with organ dysfunction
Call Microbiology before initiating treatment.
Recommended total duration: Varies with organism & severity.
Likely organisms: Streptococci, Staphylococci
- If asked to start gentamicin, use Synergistic Gentamicin protocol. Do not use the standard gentamicin chart.
- If endocarditis confirmed antimicrobial treatment is likely to be several weeks; consider siting a midline or PICC.
- The purpose of separate blood cultures in time and site is to identify a persisting bacteraemia, a hallmark of endocarditis.
- In prosthetic valve endocarditis if the diagnosis is unclear after 3 sets, consider taking a further 3 sets of blood cultures.