Recommended total duration: 14 days from first negative blood culture after antifungals have been started, if no metastatic foci, and symptoms have resolved.

Risk factors include: GI surgery, diabetes mellitus, central vascular catheters, TPN, and urinary tract manipulation or surgery including stents.

For further information see SAPG guidance here. 

  • Blood cultures: every 48h until documented clearance of Candida from blood
  • Dilated fundoscopic examination: Preferably by an ophthalmologist, within 7 days of diagnosis
  • Other investigations are dictated by likely source of Candida, and metastatic spread to other sites. Correlate with patient symptoms.
  • HIV screen

All cases will be managed in conjunction with an infection specialist. Advice can be found here.

Consider if the following criteria are met:

  • Minimum of 5 days IV therapy
  • Clinically stable
  • Repeat blood culture negative
  • Isolate is susceptible to oral agent