Cellulitis - Spreading or severe sepsis

First Line

Important: Therapy

Flucloxacillin IV + Amoxicillin IV + Clindamcyin IV for 7-14 days

Notes:

Second line: mild intolerance or mild skin reaction

Important: Therapy

Ceftriaxone IV + Clindamycin IV for 7-14 days

Notes:

Anaphylaxis to penicillin / cephalosporins (severe allergy) or MRSA - (Penicillin allergy)

Important: Therapy

Vancomcyin IV + Clindamycin IV for 7-14 days

Notes:

Important: Notes

Discuss with microbiology for IV to oral switch