PPIs
Patients may be prescribed a 3-month course of PPI therapy post-operatively, eg:
- Initial dose: lansoprazole oro-dispersible tablet, 30mg once daily.
- Maintenance dose, when patient is managing solid foods: lansoprazole capsules, 15mg once daily.
NSAIDS
Avoid prescribing drugs that irritate the gastric mucosa such as non-steroidal anti-inflammatory drugs (NSAIDS). Even in the presence of a PPI these drugs should be avoided long-term due to increased risk of stomal bleeding, stomal ulceration and anastomotic stricture.
Medication review for all patients post bariatric surgery
Non-solid oral dosage forms:
In the first few weeks after surgery, liquid or crushed preparations will be required until the patient is managing solid food (generally 6 to 8 weeks).
- Information on alternative formulations: Drug Administration via Enteral Feeding Tubes via Medicines Complete. Or for queries, contact pharmacy.
- If liquid preparations are used, they should be low sugar to reduce the risk of dumping syndrome.
- It is recommended to avoid effervescent formulations as any additional gas in the stomach pouch can cause discomfort, nausea and vomiting.
Modified Release
Slow-release and enteric coated medications may not be fully absorbed after bariatric surgery.
Special patient populations:
As the absorption of medication may be altered after bariatric surgery, patients who are on medication with a narrow therapeutic index or with conditions that need close control, such as epilepsy, may need input from their specialist teams.
- Epilepsy: Close monitoring of condition is required.
- Diabetes: In people with type 2 diabetes, blood sugars may drop rapidly after bariatric surgery. Medications often need to be reduced or stopped, alongside increased monitoring of blood
- Hypertension: Blood pressure will also decrease with weight loss. Weight loss will be more rapid in the initial weeks post-op due to reduced intake and medication should be adjusted accordingly.