THIAMINE (VITAMIN B1)

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Tablets 50mg, 100mg

Dosage:

  • Mild deficiency: 25mg daily
  • Severe deficiency: 200mg to 300mg daily in divided doses.
  • Patients with alcohol dependence: should be prescribed oral thiamine 200mg to 300mg daily in divided doses:
    • before planned withdrawal of alcohol
    • during acute withdrawal of alcohol
    • for up to 12 months after acute withdrawal of alcohol, indefinitely in some cases
    • for patients not undergoing alcohol withdrawal but at high risk of developing Wernicke's encephalopathy.

PYRIDOXINE (VITAMIN B6)

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Tablets 10mg, 50mg

Dosage:

  • Deficiency: 20 to 50mg up to 3 times daily.
  • Isoniazid induced neuropathy:
    • Prophylaxis: 10mg daily
    • Treatment 50mg 3 times daily. 
  • Idiopathic sideroblastic anaemia: 100 to 400mg daily in divided doses.

Notes:

  • The use of pyridoxine in premenstrual syndrome off-label is of doubtful value.
  • Overdosage induces toxic effects.

PARENTERAL VITAMINS B AND C

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

High potency injection (Pabrinex®) intravenous, intramuscular

Dosage:

Notes:

06/09/24: There is a known shortage with this product see: Medicines shortage log (NHS Highland intranet access required)

VITAMIN B COMPLEX

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Vitamin B compound strong tablets nicotinamide 20mg, pyridoxine hydrochloride 2mg, riboflavin 2mg, thiamine hydrochloride 5mg (Restricted: Hospital use only)

Dosage:

Prescriptions are for a maximum of one month.

Editorial Information

Document Id: F317