TAM (Treatments and Medicines) NHS Highland
Important: Therapy notes
Important: Formulation and dosage details
Formulation:
Infusion 1 gram (Protected antibiotic to be prescribed on the advice of an infection specialist only)
Other beta-lactam antibiotics for specialist use (Formulary: Infections)
Use only in accordance with protocols or on advice of Microbiology, Infectious Diseases or appropriate Consultant Specialist.
Important: Therapy notes
Important: Formulation and dosage details
Formulation:
Injection 500mg, 1 gram (Protected antibiotic to be prescribed on the advice of an infection specialist only)
Important: Therapy notes
Important: Formulation and dosage details
Formulation:
Powder for solution for infusion 1g/1g (Protected antibiotic to be prescribed on the advice of an infection specialist only)
Dosage:
As per SMC 2278: for the treatment of the following infections in adults:
- Complicated urinary tract infection (cUTI), including pyelonephritis
- Complicated intra-abdominal infection (cIAI)
- Hospital-acquired pneumonia (HAP), including ventilator associated pneumonia (VAP)
Treatment of patients with bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed above.
Meropenem/vaborbactam is also indicated for the treatment of infections due to aerobic Gram-negative organisms in adults with limited treatment options.
SMC restriction: for adults with confirmed carbapenem-resistant Enterobacteriaceae (CRE), which
is involved in the production of Klebsiella pneumoniae carbapenemase (KPC) associated with cUTI
(including acute pyelonephritis [AP]), cIAI, HAP (including VAP) and bacteraemia that occurs in association with, or is suspected to be associated with any of the infections previously mentioned.
Use should be on the advice of local microbiologists or specialists in infectious disease.