GENTAMICIN

Important: Therapy notes

MHRA advice: Aminoglycosides (gentamicin, amikacin, tobramycin, and neomycin): increased risk of deafness in patients with mitochondrial mutations (January 2021) (www.gov.uk).

Important: Formulation and dosage details

Formulation:

Injection 20mg/2mL, 80mg/2mL

Dosage:

Follow local hospital guidelines, monitor drug levels, see:

  • gentamicin prescribing, administration and monitoring chart
  • gentamicin dose calculator
  • Policy for use of intravenous gentamicin as part of the management of infective endocarditis in adults
  • For surgical prophylaxis – see dosing table and give as a single dose (no monitoring).

Editorial Information

Document Id: F256