Carbonic anhydrase inhibitors and systemic drugs for the eye (Formulary)

ACETAZOLAMIDE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Tablets 250mg (s)

Dosage:

By mouth, 250mg to 1 gram daily in divided doses.

Important: Formulation and dosage details

Formulation:

Modified release capsules 250mg (s)

Dosage:

By mouth, 250mg to 1 gram daily in divided doses.

Important: Formulation and dosage details

Formulation:

Injection 500mg (s)

BRINZOLAMIDE WITH BRIMONIDINE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Eye drops (brinzolamide 10mg/mL, brimonidine tartrate 2mg/mL) (s)

Dosage:

Apply 1 drop twice daily.

BRINZOLAMIDE

Important: Therapy notes

May be useful where there is intolerance to dorzolamide eye drops due to stinging.

Important: Formulation and dosage details

Formulation:

Eye drops 10mg/mL (s)

Dosage:

Apply 1 drop twice daily increased to 3 times daily if necessary.

BRINZOLAMIDE WITH TIMOLOL

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Eye drops (brinzolamide 10mg/mL, timolol 5mg/mL) (s)

Dosage:

Apply 1 drop twice daily.

DORZOLAMIDE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Eye drops 2% (s)

Dosage:

Used alone, apply 1 drop 3 times daily; with topical beta-blocker, apply 1 drop twice daily.

Important: Formulation and dosage details

Formulation:

Preservative-free eye drops 2% (s)

Dosage:

Used alone, apply 1 drop 3 times daily; with topical beta-blocker, apply 1 drop twice daily.

DORZOLAMIDE WITH TIMOLOL

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Eye drops (dorzolamide 2%, timolol 0·5%) (Restricted: specialist recommendation only)

Dosage:

Apply 1 drop twice daily.

Important: Formulation and dosage details

Formulation:

Preservative-free eye drops multidose 5mL (dorzolamide 2%, timolol 0·5%) (Restricted: specialist recommendation only)

Dosage:

Apply 1 drop twice daily.

Notes:

These are a more cost-effective alternative that is better for the environment than the single use drops.

Important: Formulation and dosage details

Formulation:

Preservative-free eye drops single use 60 unit (dorzolamide 2%, timolol 0·5%) (Restricted: specialist recommendation only)

Dosage:

Apply 1 drop twice daily.

Editorial Information

Document Id: F211