Very potent corticosteroid (Formulary)

Refer to guidance on Use of topical corticosteroids and Management of eczema/dermatitis.
Prescribe by generic name whenever possible.

Please consider if a steroid emergency card needs to be given to the patient alongside the traditional steroid treatment card.  This is to support the timely recognition and treatment of potential adrenal crisis and is suitable for some patients on oral, inhaled, topical or rectal steroids.  For more information, including which patients should receive the card, see HIS for details.  Steroid emergency cards have been distributed to, hospitals, GP surgeries and community pharmacies. Primary care can order replacement cards from 01463 706886.

MHRA advice: Topical corticosteroids: introduction  of new labelling and reminder of the possibility of severe side effects, including Topical Steroid Withdrawal Reactions (May 2024) (www.gov.uk).
MHRA advice: Topical corticosteroids: information on the risk of topical steroid withdrawal reactions (September 2021) (www.gov.uk).

See Peri-operative guidelines for patients with or at risk of adrenal insufficiency

CLOBETASOL PROPIONATE

Important: Therapy notes

  • Not recommended for first-line use. 
  • Avoid in children. 
  • Use must be reviewed by prescriber at least monthly, it should never be on repeat prescription except for use in special circumstances, eg vulval lichen sclerosus; see Vaginal and vulval conditions and guidance on use of topical corticosteroids.

Important: Formulation and dosage details

Formulation:

Cream (Dermovate®, ClobaDerm®) 0·05%

Important: Formulation and dosage details

Formulation:

Ointment (Dermovate®, ClobaDerm®) 0·05%

Editorial Information

Document Id: F149