Drugs affecting the immune response for eczema (Formulary)

Important: Formulation and dosage details

Formulation:

Tablets film-coated 50mg, 100mg and 200mg (hospital use only)

Dosage:

As per SMC 2431: for the treatment of moderate-to-severe atopic dermatitis in adults and adolescents 12 years and older who are candidates for systemic therapy.
SMC restriction: for use in patients who have not responded to, or have lost response to, at least one systemic immunosuppressant therapy, or in whom these are contraindicated or not tolerated.

Homecare is the preferred option - contact nhsh.homecare@nhs.scot

Important: Formulation and dosage details

Formulation:

Solution for injection pre-filled syringe 300mg (specialist use only)

Dosage:

Subcutaneous injection. Initially 600mg, followed by 300mg every 2 weeks, the initial dose should be administered as two consecutive 300mg injections at different injection sites, review treatment if no response after 16 weeks.

Homecare is the preferred option - contact nhsh.homecare@nhs.scot.

Important: Formulation and dosage details

Formulation:

Solution for injection in pre-filled syringe 150mg (specialist initiation only)

Dosage:

• Third line. (Second line biologic therapy).
• See SMC advice 2403.

Important: Formulation and dosage details

Formulation:

Tablets prolonged-release 15mg, 30mg (hospital use only)

Dosage:

As per SMC 2417.
Homecare is the preferred option - contact nhsh.homecare@nhs.scot

Notes:

For doses of 30mg patients should be prescribed 1 x 30mg tablet and not 2 x 15mg tablets.  This is a more cost-effective option.