Anti-infective preparations used topically (Formulary)

HYDROGEN PEROXIDE

Important: Therapy notes

Please note: this medicine is only used topically.

  • MHRA advice: Hydrogen peroxide: reminder of risk of gas embolism when used in surgery (December 2014) (www.gov.uk).

Important: Formulation and dosage details

Formulation:

Cream 1%

Dosage:

  • First line treatment of non-bullous impetigo.

METRONIDAZOLE

Important: Therapy notes

Please note: this medicine is also used systemically. 

  • Cream is preferable to gel. 

Important: Formulation and dosage details

Formulation:

Cream (Rozex®) 0·75%

Dosage:

Rosacea: apply cream thinly twice daily for up to 3 to 4 months (often very rapidly effective)

Important: Formulation and dosage details

Formulation:

Gel (Anabact®) 0·75%

Dosage:

Malodorous tumours and skin ulcers: apply gel to clean wound once or twice daily and cover with non-adherent dressing. Unsuitable for use in rosacea.

  • Avoid contact with eyes.

MUPIROCIN

Important: Therapy notes

Please note: this medicine is only used topically.

  • Mupirocin cream and ointment are not interchangeable. The prescription should specify the formulation required.

Important: Formulation and dosage details

Formulation:

Cream (Bactroban®) 2% (s)

Dosage:

Traumatic lesions secondarily infected with MRSA- cream: apply 3 times daily for up to 10 days; re-evaluate if no response after 3 to 5 days.

Important: Formulation and dosage details

Formulation:

Ointment 2% (s)

Dosage:

MRSA skin colonisation or infection - ointment: apply up to 3 times daily for up to 10 days.  May sting.

SODIUM FUSIDATE

Important: Therapy notes

Please note: this medicine is also used systemically. 

Important: Formulation and dosage details

Formulation:

Cream 2% (s)

Dosage:

Limited indications: staphylococcal skin infections, eg impetigo. Use ONLY for short periods of time (up to 10 days) to prevent bacterial resistance. 

Editorial Information

Document Id: F110