Angiotensin receptor neprilysin inhibitor (Formulary)

SACUBITRIL/VALSARTAN

Important: Therapy notes

  • If the patient is already on an ACE inhibitor, it should be stopped for 36 hours before initiating sacubitril/valsartan to minimise the risk of angioedema.

Important: Formulation and dosage details

Formulation:

Tablets 24mg/26mg, 49mg/51mg, 97mg/103mg (Entresto®) (s)

Dosage:

As per SMC 1132/16: in adult patients for treatment of symptomatic chronic heart failure with
reduced ejection fraction. 

Editorial Information

Document Id: F046