Oxytocin (Syntocinon) (598)

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Note - Oxytocin is a potentially dangerous medicine. As it is in common use this fact may not be respected. Misuse of Oxytocin in Labour is a common criticism in Obstetric litigation. Prolonged intravenous administration at high doses with large volume of fluid (as possible in inevitable or missed abortion or post partum haemorrhage) may cause water intoxication with hyponatraemia. To avoid: use electrolyte containing diluent (i.e. not glucose) increase oxytocin concentration to reduce fluid, restrict fluid intake by mouth; monitor fluid and electrolytes.Indications:

  1. Management of third stage labour (unlicensed obstetric use).
  2. Induction of labour - separate doses for primigravida women, parous women and those women undergoing vaginal birth after Caesarean section.
  3. Augmentation of labour - separate doses for primigravida women, parous women and those women undergoing vaginal birth after Caesarean section.
  4. Delivery of second twin
  5. Caesarean section as prophylaxis against PPH
  6. Postpartum Haemorrhage.
  7. Incomplete, inevitable, or missed abortion

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Editorial Information

Last reviewed: 25/10/2017

Next review date: 31/07/2023

Author(s): Julie Murphy.

Version: 2

Approved By: Obstetrics Clinical Governance Group

Document Id: 598