• Opioid analgesics should not be used to sedate dying patients.
  • If sudden increase in pain or agitation occurs exclude urinary retention or other reversible causes.
  • SC infusions of medication provide maintenance treatment only. Additional doses of medication by SC injection will be needed if the patient’s symptoms are not controlled, or when starting an SC infusion in an unsettled patient.
  • Midazolam SC infusions are usually titrated in 5mg to 10mg steps. Single SC doses usually last 1 to 2 hours. Useful as an anticonvulsant.
  • Consider a nicotine replacement patch in heavy smokers with withdrawal symptoms.