Colon capsule endoscopy (CCE-2) for the detection of colorectal polyps and cancer in adults [In development]

SHTG logo

SHTG recommendation

In response to enquiry from Scottish Government

What were we asked to look at

The Scottish Health Technologies Group (SHTG) was asked to assess the clinical and cost effectiveness of PillCam™ Colon-2 (second-generation colon capsule endoscopy (CCE-2)), compared with optical colonoscopy or computed tomographic colonography (CTC), for identifying colorectal polyps in adults with signs or symptoms of colorectal cancer or at increased risk of colorectal cancer.

Why is this important

In 2018, Evidence Note 86 examined the evidence for CCE-2. Since then further evidence assessing the effectiveness of CCE-2 has been published.
A project between the Scottish Government and CCE-2 industry colleagues, called the Scottish Capsule Programme (SCOTCAP), aimed to ease pressure on waiting times for optical colonoscopy. SCOTCAP was delivered in the North of Scotland and was a feasibility and acceptability trial of the use of CCE-2 in the community. In order to inform decision making surrounding the rollout of SCOTCAP across Scotland, the Scottish Government asked SHTG to reassess the CCE-2 evidence