Definitions and abbreviations
Definitions
Biofilm: a slime-enclosed community of bacterial colonies that is very difficult to eradicate even with the most powerful antibiotics or sterilising systems.37
Ecthyma: a pus forming, ulcerating and crusting inflammatory skin disease.38
Endotoxin: a toxin produced by certain bacteria and released upon destruction of the bacterial cells.39
Ex vivo: in an artificial environment outside a living organism.40
Furunculosis: a condition in which the patient suffers from recurrent episodes of boils.41
Hepatalgia: pain in the liver.42
Hidradenitis: inflammation of a sweat gland.43
Lytic: of or relating to lysis; the destruction of a living cell by disruption of its membrane.44
Paronychia: infection of the skin fold at the base or side of the nail.45
Pyoderma: a pus containing skin infection.46
Sycosis vulgaris: a chronic inflammation of the hair follicles, especially of the beard, characterised by eruption of pimples and nodules.47
Abbreviations
ARLG | Antibacterial Resistance Leadership Group |
CPI | consumer price index |
CS | case studies |
DFI | diabetic foot infection |
DFU | diabetic foot ulcer |
DNA | deoxyribonucleic acid |
ESKAPE | Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baummannii, Pseudomonas aeruginosa, and Enterobacter species |
FRI | fracture-related infection |
GMP | Good Manufacturing Process |
GRADE | Grading of Recommendations, Assessment, Development and Evaluations |
ICER | incremental cost effectiveness ratio |
LEA | lower extremity amputation |
MHRA | Medicines and Healthcare Products Regulatory Authority |
NA | not applicable |
NHS | National Health Service |
NICE | National Institute of Health and Care Excellence |
NR | not reported |
OBS | observational trial |
PFU | plaque forming units |
PJI | periprosthetic joint infection |
PSSRU | Personal and Social Services Research Unit |
PT | phage therapy |
QALY | quality-adjusted life-year |
RCT | randomised controlled trial |
SHTG | Scottish Health Technologies Group |
SoC | standard of care |