Cumulative toxicity tool and adverse drug reactions (ADR) | Right Decisions

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Cumulative toxicity tool and adverse drug reactions (ADR)

Please update your RDS mobile app to version 4.7.1

We are pleased to advise that deep linking capability, enabling users to directly download individual mobile toolkits, has now been released on the RDS mobile app. When you install the update, you will see that each toolkit has a small QR code icon the header area beside the search icon – see screenshot below. Clicking on this icon will open up a window with a full-size QR code and the alternative of a short URL for sharing with users. Instructions are provided.

You may need to actively install the update to install RDS app version 4.7.1 to see this improvement. Installing this update is also strongly recommended to get the full benefits of the new contingency arrangements – specifically, that if the RDS website should fail, you will still be able to download new mobile app toolkits.

To check your current RDS version, click on the three dots bottom right of the RDS app screen. This takes you to a “More” page where you will see the version number. To install latest updates:

On iPhones – go to the Apple store, click on your profile icon top right, scroll down to see the apps waiting to be updated and update the RDS app.

On Android phones – these can vary, but try going to the Google Play store, click on your profile icon top right, click on “Manage apps and device”, select and update the RDS app.

Please get in touch with ann.wales3@nhs.scot with any questions.

The chart below cross-tabulates medication and Adverse Drug Reaction (ADR) risks associated with them.It can help identify actual ADRs and the risk of developing them. It identifies where an ADR may be due to a cumulative effect. Generally, the shaded areas represent side effects which are listed in SPCs as having an incidence greater than 1 in 10,000 (where the incidence is listed), or from knowledge of the mode of action of a medicine.

Please, note that the list focuses on commonly used drugs and commonly preventable ADRs, and is not meant to replace more detailed medicines information sources.

^{A -} STRONG anticholinergics are: dimenhydrinate, scopolamine, dicyclomine, hyoscyamine, propantheline; ^{B -} STRONG anticholinergics are: tolterodine, oxybutynin, flavoxate; ^{C -} STRONG anticholinergics are: amitriptyline, desipramine, doxepine, imipramine, nortriptyline, trimipramine, protriptyline; ^{D -} STRONG anticholinergics are: promethazine; ^{E -} STRONG anticholinergics are: diphenhydramine, clemastine, chlorphenamine, hydroxyzine. Please see here for full list of anticholinergics See here for full list of medicines linked to falls. ^F- Amiloride side effect frequency unknown