Study population:

Secondary prevention in patients at high risk of cardiovascular events.

Included patients with previous MI, acute MI, previous stroke/TIA, and other high risk (excluding acute stroke)

Comments:

Antiplatelets included aspirin (most widely studied), clopidogrel, dipyridamole, and other antiplatelets not commonly used in UK practice.

Outcome Duration NNT Annualised NNT

Serious vascular event. (Defined as non-fatal MI, non-fatal stroke or vascular death).

26 months

 15

32

References

Antithrombotic trialists collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, MI and stroke in high risk patients. BMJ 2002;358:71-86