CAUTION: Hyperkalaemia. Risk factors include CKD (CI if eGFR<30ml/min), dose >25 mg daily , co-treatment with ACEI/ARBs, amiloride, triamterene, potassium supplements
Recommended in moderate to severe CHF: See NNT table
CAUTION: Hyperkalaemia. Risk factors CKD, combination with ACEI/ARB, triamterene, amiloride
CAUTION: AKI. Avoid combination with NSAIDs and advise patient to stop when at risk of dehydration