Antibacterials (Oral) - Nitrofurantoin

Evidence of no benefit for treating asymptomatic bacteriuria (ASB) in diabetes or older adults

Review use of long term antibiotics for recurrent UTI (every 6 months)

Lack of evidence for antibiotic use in preventing catheter-associated ASB

Need

CAUTION: Pulmonary/renal ADRs; avoid in renal impairment; contraindicated if eGFR<30ml/min

Safety

Antifungals

CAUTION: Risk of exacerbation of heart failure with azole antifungals.

CAUTION: Many serious drug interactions with azole antifungals.

Safety