Antibiotics for confirmed meningitis

  • Meningococcus: IV Ceftriaxone for 7 days
  • H influenzae: IV Ceftriaxone for 10 days
  • S pneumoniae: IV Ceftriaxone for 14 days, add vancomycin if resistant strain.
  • Group B Strep: IV Cefotaxime for at least 14 days.
  • L monocytogenes: IV amoxicillin or ampicillin for 21 days in total, plus IV gentamicin for at least the first 7 days.
  • Gram-negative bacilli: IV cefotaxime for at least 21 days (unless alternative directed by local antimicrobial resistance patterns or specific sensitivities). 

Duration may be dictated by clinical response – discuss with infectious disease specialist.

Long-term management:

  • Before discharge consider need for aftercare, discuss potential long-term effects with parents, arrange hearing test.
  • Refer children with severe or profound deafness for cochlear implant assessment ASAP.
  • Use Meningitis Research Foundation (2020) Discharge checklist
  • Provide MRF (2019) Your guide and direct to meningitis support organisations MRF (2022) After effects or Meningitis Now (n.d.) Your guide and my journal.
  • Offer further care on discharge as needed.
  • Paediatrician to review child with results of their hearing test 4-6weeks after discharge from hospital considering all potential morbidities and offer referral.
  • Inform GP, health visitor or school nurse.
  • Notify public health
  • Follow up prophylaxis for household contacts. See MRF (2018) Management of meningococcal disease in children and young people.