Appendix 2: Piperacillin/tazobactam dose banding chart (1 month - 18 years)
NHS Dumfries & Galloway Antimicrobial Handbook
Recommended piperacillin/tazobactam dosing schedule (1 month - 18 years)
Normal renal function assumed.
Dosing schedule should be reviewed/adjusted in reduced renal function - refer to BNFc and/or liaise with Pharmacist.
Piperacillin/tazobactam can be administered by intravenous infusion or bolus (i.e. injection over 5 minutes, off label), as per Medusa.
|
Patient’s weight (kg) |
Each dose (mg), |
|
4.1 – 4.5 |
375 |
|
4.6 – 5.4 |
450 |
|
5.5 – 6.2 |
525 |
|
6.3 – 7.0 |
600 |
|
7.1 – 7.9 |
675 |
|
8.0 – 8.7 |
750 |
|
8.8 - 9.5 |
825 |
|
9.6 – 10.9 |
900 |
|
11.0 – 12.4 |
1050 |
|
12.5 – 14.1 |
1200 |
|
14.2 – 15.8 |
1350 |
|
15.9 – 17.4 |
1500 |
|
17.5 – 19.1 |
1650 |
|
19.2 – 20.8 |
1800 |
|
20.9 – 22.4 |
1950 |
|
22.5 – 24.1 |
2100 |
|
24.2 – 25.8 |
2250 |
|
25.9 – 27.4 |
2400 |
|
27.5 – 29.1 |
2550 |
|
29.2 – 30.8 |
2700 |
|
30.9 – 32.4 |
2850 |
|
32.5 – 34.1 |
3000 |
|
34.2 – 35.8 |
3150 |
|
35.9 – 37.4 |
3300 |
|
37.5 – 39.1 |
3450 |
|
39.2 – 40.8 |
3600 |
|
40.9 – 42.4 |
3750 |
|
42.5 – 44.1 |
3900 |
|
44.2 – 45.8 |
4050 |
|
45.9 – 47.4 |
4200 |
|
47.5 – 49.1 |
4350 |
|
> 49.2 |
4500 |
Based on table produced by NHS Greater Glasgow and Clyde.