Starting dose: 1mg daily.
Dose escalation: No more than 1mg per week.
Maximum dose: Maximum dose should not exceed 0.12mg/kg.
Age |
Weight (kg) |
Maximum dose |
6-12 |
≥25 |
4mg |
13-17 |
34 to 41.4 |
4mg |
13-17 |
41.5 to 49.5 |
5mg |
13-17 |
49.5 to 58.4 |
6mg |
13-17 |
≥58.5 |
7mg |
Adult* |
≥58.5 |
7mg |
*Unlicensed
Dose should be reduced by half if concurrent use with moderate or potent inhibitors of CYP3A4 and ciprofloxacin.