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Pregnancy Testing in Gynaecology patients (316)

Warning

Objectives

To standardise practice in testing for pregnancy in women attending gynaecology

Scope

When to perform pregnancy testing in women undergoing procedures, investigations, treatments and surgical procedures in the inpatient and outpatient setting including those undergoing general anaesthetic

Audience

All Healthcare workers involved in the care of women where pregnancy status would affect care

Please report any inaccuracies or issues with this guideline using our online form

All patients of childbearing potential (biologically female and aged 12 - <55 years of age) should have pregnancy status determined prior to undergoing anaesthetic, some radiological investigations, surgery under general anaesthetic, or a procedure which may lead to potential disruption of a pregnancy through instrumentation of the uterus.

Pregnancy status should also be determined in women when presenting as an emergency to hospital where pregnancy may determine diagnosis or affect management of these women.

For further details regarding pregnancy testing in girls aged 12-16 years of age, please refer to the RHC guideline Pregnancy testing guidelines for girls aged 12 yrs & over (RHC) 

This guidance is mandatory – every eligible patient must be assessed, every time.

Gaining Consent

NICE suggest that on the day of the procedure or at time of presentation, all women of childbearing potential should have a sensitive discussion as to whether there is any possibility they could be pregnant.  The healthcare professional, should make the patient aware of the risks that both the anaesthetic and the procedure itself can have on the developing pregnancy.

Permission should be sought from the patient to perform the test.  Covert pregnancy testing should not be undertaken as it can be viewed as an infringement of human rights.  Discussions regarding pregnancy testing should be documented in notes.

Routine Urine Pregnancy Testing versus Enquiry Based Assessment

There are two possible options for ascertaining pregnancy status in female patients; consented urine pregnancy testing or Enquiry Based Assessment.

The urine pregnancy test should be considered as first line approach and can be used in conjunction with enquiry based approach.  In cases when urine testing is not possible, practical or feasible, e.g. adults with incapacity, enquiry based assessment alone should be performed and documented.

Information for Enquiry Based assessment includes

  • First day of Last Menstrual Period (LMP)
  • Current contraception and usage
  • Date of last episode of unprotected Sexual Intercourse (UPSI)

The criteria for excluding pregnancy used by the Faculty of Sexual and Reproductive Health is outlined below.

Criteria for excluding pregnancy (adapted from UK Selected Practice Recommendations for Contraceptive Use) 3

Health professionals can be ‘reasonably certain’ that a woman is not currently pregnant if any one or more of the following criteria are met and there are no symptoms or signs of pregnancy: 

  • She has not had intercourse since last normal menses
  • She has been correctly and consistently using a reliable method of contraception
  • She is within the first 7 days of the onset of a normal menstrual period
  • She is not breastfeeding and less than 4 weeks from giving birth
  • She is fully breastfeeding, amenorrhoeic, and less than 6 months’ postpartum
  • She is within the first 7 days post-abortion or miscarriage.

Who should participate in testing?

  • Patient who present to emergency gynaecology services
  • Patients attending for radiological investigations excluding ultrasound
  • Patients undergoing general anaesthetic, including non-gynaecological procedures
  • In the outpatient gynaecology setting, when undertaking procedures where there is instrumentation of the uterus pregnancy status should be determined.  This would include hysteroscopy, pipelle endometrial biopsy, insertion or removal of intrauterine contraceptive devices and LLETZ procedures.
  • Consideration should be given to pregnancy testing prior to administration of hormonal therapies such as contraception or GnRH analogues.

Who is exempt from testing?

The only patients who can be excluded are as follows:

  • Previous total hysterectomy
  • Patients attending for procedure where pregnancy already confirmed e.g. TOP patients, patients management of a miscarriage including MVA and patients undergoing management of ectopic pregnancy

In women where there is contraception use, HRT use and women who are post-menopausal and <55years of age, testing should still be considered and carried out.

How is the test carried out?

Testing should be carried out on the day of the procedure, using a sample collected on admission for the procedure.  High sensitivity urine pregnancy tests should be used which will identify HCG >25iu/l.

The result of the pregnancy test must be recorded in the peri-operative care plan or in the patient notes.  It should include the test kit lot number.

In the theatre setting, the operating surgeon and theatre staff must be informed of any positive result prior to theatre transfer.  The test result, positive or negative, must be included in the surgical pause.

Limitations of Urine pregnancy Testing

It should be acknowledged that the Urine Pregnancy Test adds weight to exclusion of pregnancy, but only if ≥ 3 weeks since UPSI.

Clinicians should consider the risk of becoming pregnant if UPSI < 7 days.  In these cases an assessment should be made with regard to continuing with the planned procedure or rearranging.

Pregnancy test flow chart

Risk of pregnancy flow chart

This guidance is mandatory – every eligible patient must be assessed, every time.

Editorial Information

Last reviewed: 10/06/2024

Next review date: 31/03/2028

Author(s): Dr Claire Higgins, Consultant Obstetrics and Gynaecology.

Version: 3

Approved By: Gynaecology Clinical Governance Group

Document Id: 316

References

1. NHSGGC, Pregnancy testing guidelines for girls aged 12 yrs & over (RHC)

2. Routine preoperative tests for elective surgery, NICE guideline, [NG45] Published April 2016

3. Faculty of Sexual and Reproductive Healthcare, Clinical Guidance, Intrauterine Contraception, April 2015, (amended September 2019).

4. Alere TM HCG Casette (25mIU/ML), Product information sheet