Where patients have missed methadone doses, a change of tolerance or increased drug use may occur. In this situation, follow the guidance below:

Tolerance may have reduced

 

Number of missed days

Action to be taken

One day No change to dose
Two or three days No change to dose
More than three days A dose reduction may be required. Contact DLN for advice on dose titration (refer to Useful phone numbers and contacts during working hours)

Overview of Inpatient substance misuse pathway

 

Editorial Information

Author(s): Linda Smith, Rakhee Vasishta, Joanna Renée.

Approved By: NHS Lothian Drugs and Therapeutics Committee

Reviewer name(s): Linda Smith, Rakhee Vasishta, Joanna Renée.