Warning

Patients with hepatitis C virus (HCV) infection can be managed within the Hepatology services at the Royal Infirmary of Edinburgh, or the Regional Infectious Diseases Unit at the Western General Hospital.

Some treatment clinics are run jointly with Substance Misuse Directorate, primary care health centres, and pharmacies.​

HCV testing

Hepatitis C antibody testing 

  • Hepatitis C antibody testing is performed as the initial screening test (4.9mL brown capped gel tube). ​

Hepatitis C RNA PCR

  • If the patient is already known to be HCV antibody positive, please send HCV RNA quantitative PCR to confirm active infection (9mL (or 2 x 2.6mL) red cap EDTA tubes).​
  • The lab will reflexively test HCV PCR on all new HCV antibody positive samples.​

 

Who to refer

Refer in-patients who are hepatitis C PCR positive (active infection) to the Hepatitis C team, for consideration of inpatient treatment or outpatient follow up​.

 

Do not refer patients who are hepatitis C antibody positive with a negative PCR as this suggests they have cleared the infection. No active follow up is required unless there is established liver disease.

 

Treatment overview

  • Treatment of HCV is well tolerated and highly effective
  • Almost 100% of infections are cured by tablets taken once daily for 8-12 weeks.
  • All patients with evidence of active HCV infection should be referred for consideration of antiviral treatment, particularly as this reduces risk of onwards transmission.

Referring for treatment as an inpatient​

To refer for consideration of inpatient treatment please contact the HCV team:​

RIE site referrals: RIE.HepatitisC@nhs.scot​

Western general site referrals:Loth.WGHHepatitisCTeam@nhs.scot

 

HCV drug interaction checker

When prescribing new medications to patients on treatment for hepatitis C please use this HCV drug interaction checker 

Editorial Information

Last reviewed: 27/06/2024

Next review date: 26/06/2025

Author(s): Dr Callum Mutch, Dr Dáire O'Shea.

Version: 1.0

Reviewer name(s): Dr Callum Mutch, Dr Dáire O'Shea.