Rabies post exposure risk assessment

Warning

Rabies risk assessment

This guidelines are intended for use by healthcare professionals assessing for Rabies risk following potential exposure.

The full guidelines can be accessed here: Rabies post-exposure treatment: management guidelines - GOV.UK (www.gov.uk)

 

1. What is the rabies risk of the animal involved?​

 Bats

  • In the UK/Ireland = Low risk animal
  • Outside the UK/Ireland = High risk animal

Primate or rodent

  • Low risk animals

Other terrestrial animal (e.g. dog etc)

  • Country dependent risk
  • Search and select country from Gov.uk list

2. What is the nature of exposure?

Categories for bats

Category 1 - No physical contact with the bat’s saliva

e.g. touching a dead bat, touching a bat with protective barrier/clothing, a bat in the same room as a person in the UK or Ireland

 

Category 2 - Uncertain physical contact

e.g. handling live bat without protective clothing, bat becoming tangled in hair, potential contact with a bat in the UK/Ireland in someone who is unable to give accurate and reliable history of exposure, any bat found in the room of a sleeping person outside of the UK/Ireland

 

Category 3 - Direct contact with saliva

e.g. all bites or scratches, contamination of mucous membranes with saliva or urine.

 

Categories for all other animals

Category 1 - No physical contact with saliva

e.g. touching, stroking or feeding animals

 

Category 2 - Minimal contact with saliva and/or unable to infiltrate wound with HRIG if needed

e.g. bruising or abrasions, licks to broken skin, scratches, bites which do not break the skin

 

Category 3 - Direct contact with saliva

e.g. severe or deep lacerations, bites that break the skin, contact of mucous membranes with saliva e.g. licking of mouth/lips

3. Composite rabies risk table*

*Note: If you are using a mobile phone to view this content, turn it to landscape to view the tables better

 

Country or animal risk Category 1 exposure Category 2 exposure Category 3 exposure
No risk Green Green Green
Low risk Green Amber Amber
High risk Green Amber Red
Confirmed rabid animal* Green or amber Red Red

*Advice should be sought from on-call Infectious Diseases via NHS Lothian switchboard.

4. Post-exposure treatment based on composite rabies risk and vaccine status

 

  Post-exposure treatment
Composite rabies risk Non-immunised or partially immunised Fully immunised Immunosuppressed
Green None None None
Amber doses of vaccine d0 d3, d7, d21 2 doses of vaccine do, d3-7 HRIG and 5 doses of vaccine d0, d3, d7, d14 and d30*
Red HRIG* and 4 doses of vaccine d0 d3, d7, d21 2 doses of vaccine do, d3-7 HRIG and 5 doses of vaccine d0, d3, d7, d14 and d30*

 * HRIG is not required more than seven days after the first dose of vaccine, or more than one day after the second dose. HRIG is not required for partially immunised patients (unless immunosuppressed).

5. How arrange PEP in NHS Lothian

If risk assessment recommends post-exposure rabies vaccination or HRIG:

  1. Contact the RIDU registrar on-call in hours (0900-1900) to arrange vaccination. 
  2. Rabies vaccine is also available via Emergency Departments at RIE and SJH for high risk injuries out-of-hours.

 

For very high risk exposures, such as severe and multiple bites to the head and neck or injury from a confirmed rabid animal treatment must be started as soon as possible and within 12 hours of reporting

  1. Contact the RIDU registrar on-call in hours (0900-1900) 
  2. Out-of-hours the patient should be directed to the Emergency Department for urgent treatment
  3. Additional advice can be sought from the ID consultant on-call if required.

 

Editorial Information

Last reviewed: 26/06/2024

Next review date: 26/06/2025

Author(s): Dr Callum Mutch, Dr Jan Engel, Dr Oliver Koch.

Version: 1.0

Reviewer name(s): Dr Callum Mutch.