Risks when the index is known to have HIV

The patient may know that the index partner has HIV. Where the index partner has been on anti retroviral treatment (ART) for at least 6 months with an undetectable plasma HIV viral load (HIV VL) at the time of last measurement & that measurement was within the last 6 months and with good adherence, PEP is not recommended for any exposure.

The index patient's viral load status and ART history should be confirmed with their HIV specialist. This can only be done with consent from the index patient. Where it is not possible to confirm this, PEP decisions should then be made assuming the patient has a ‘detectable viral load’.

In patients cared for in Scotland D&G viral loads below 40 copies/ml are reported as undetectable. Other services may define loads up to 200 copies/ml as undetectable. It is important to explore with the index patient’s clinic how they define undetectable and whether the results would indicate if PEP is needed.

If the viral load is detectable/not known HIV PEP is recommended if the patient gave or received anal sex or received vaginal sex without a condom (or the condom burst/ came off). In some circumstances it may also be considered if patient performed insertive vaginal sex on an HIV positive index partner. See PEP for HIV: Quick guidance for risk assessment & initial management.