Recommended antibiotic |
Ceftriaxone 2g IV 12 hourly PLUS Metronidazole 400mg every 8 hours orally (500mg every 8 hours IV if oral route unavailable) If MRSA positive ADD Vancomycin IV (use NHS Lothian Calculator on AMT intranet page); aim trough levels 15-20mg/L |
Severe penicillin allergy |
Vancomycin IV (use NHS Lothian Calculator on AMT intranet page); aim trough levels 15-20mg/L PLUS Ciprofloxacin 400mg IV 8 hourly * PLUS Metronidazole 400mg every 8 hours orally (500mg every 8 hours IV if oral route unavailable) |
*Avoid fluoroquinolones if taking steroids and the elderly. Review MHRA Quinolone Warning before prescribing. If an alternative agent is required please contact microbiology.