Micro Organisms

Streptococcus pyogenes, Staphylococcus aureus

Duration

Limited soft tissue infection: 7 days

Moderate to severe: 7-14 days

Limited soft tissue infection

Important: Therapy

Oral Flucloxacillin

Notes:

Limited soft tissue infection in penicillin allergy

Important: Therapy

Oral Clindamycin

Notes:

Clindamycin suspension is no longer available; clarithromycin may be used as an alternative for patients who require a liquid.

Moderate to severe

Important: Therapy

IV Flucloxacillin

switch to

Oral Flucloxacillin

Notes:

Moderate to severe in penicillin allergy

Important: Therapy

IV Clindamycin

switch to 

Oral Clindamycin

Notes:

Clindamycin suspension is no longer available; clarithromycin may be used as an alternative for patients who require a liquid.

If MRSA likely

Important: Therapy

IV Vancomycin

Notes:

Important: Notes

Send blood for culture.

Take appropriate specimens before starting therapy, consult dermatologist and medical microbiologist for patients with severe or recurrent infections.