Post-operative wound infection

Important: Therapy

• Take appropriate specimens before starting therapy, consult dermatologist and medical microbiologist for patients with severe or recurrent infections
• Consider the necessity for surgical intervention, tetanus prophylaxis and topical cleaning
• Chronic wounds such as pressure sores and leg ulcers do not require antibiotics unless there is clinical evidence of infection eg cellulitis, discharge or acute pain
• Route of administration is dependent on the severity of infection and ability of patient to take medication orally.
• If collection present will require surgical drainage

Notes:

Important: Therapy

IV /Oral Flucloxacillin 500mg - 1g 6 hourly

Notes:

Important: Therapy

Vancomycin IV as per guideline

Use calculator for intermittent dosing.

Switch to

Oral Co-trimoxazole 960mg 12 hourly 

Notes:

Important: Therapy

If IV required:

IV Co-trimoxazole* 960mg 12 hourly

+/- IV Metronidazole 500mg 8 hourly

Switch to

oral Co-trimoxazole 960mg 12 hourly

+/- oral Metronidazole 400mg 8 hourly 

Notes:

*If IV Co-trimoxazole not available or unsuitable use IV Co-amoxiclav 1.2g 8 hourly

Important: Therapy

If IV Co-trimoxazole not available or unsuitable

IV Co-amoxiclav 1.2g 8 hourly

OR if penicillin allergic

IV Clindamycin 600mg 8 hourly

Notes: