First Line

Important: Therapy

Ceftriaxone (at CNS doses) IV + Metronidazole IV/PO for 10-14 days - minimum 5 days IV

Co-amoxiclav PO for oral switch

Notes:

Anaphylaxis (including severe skin reaction) to penicillin / cephalosporins - (Penicillin allergy)

Important: Therapy

Vancomycin IV + gentamicin IV + metronidazole IV/PO

Notes:

Important: Notes

Involve ENT