First Line

Important: Therapy

Piperacillin-Tazobactam (Tazocin) 4.5g IV 6 hourly AND Gentamicin IV as per protocol AND Metronidazole 500mg IV 8 hourly

Notes:

Penicillin Allergy

Important: Therapy

Vancomycin IV as per protocol AND Gentamicin IV as per protocol AND Ciprofloxacin 400mg IV 8 hourly (consider safety issues) AND Metronidazole 500mg IV 8 hourly

Notes:

Important: Notes

If evidence of toxic shock - ADD Clindamycin 1.2g IV 6 hourly and consider IVIG