Protected Antibiotics - Permitted Indications
These antibiotics should ONLY be used for the indications listed below.
ALL OTHER USE MUST BE ON ADVICE OF CONSULTANT MICROBIOLOGIST / INFECTIOUS DISEASE CONSULTANT
Ceftazidime
- Febrile neutropenia (haematology and oncology patients only)
- Exacerbations of bronchiectasis or cystic fibrosis (if Pseudomonas colonisation/infection and penicillin allergy)
Ceftriaxone
- Only on advice of consultant clinician (except in meningitis) or Microbiology or ID consultant
- Meningitis
Clindamycin
- Group A Streptococcal sepsis/toxic shock
- Suspected or confirmed necrotising fasciitis
- Soft tissue infections in penicillin allergic patients only when benefits outweigh risk and no other option available
Levofloxacin
- As indicated in guideline in patients with true penicillin allergy
- Strong clinical suspicion of Legionella infection
Linezolid
- Only on advice of Microbiology or ID consultant
Meropenem - This may only be prescribed after consultation with senior member of clinical team
- Exacerbation of bronchiectasis/cystic fibrosis if colonisation/infection with resistant Gram negative organisms including Pseudomonas
- Febrile neutropenia (haematology/oncology patients)
- Infections with multi resistant Gram negative bacilli as indicated by sensitivity report on culture
- Severe sepsis unresponsive to Piperacillin/Tazobactam and Gentamicin
Teicoplanin
- Vancomycin intolerance
- Surgical prophylaxis (following guideline)
- Out-patient and/or home parenteral antibiotic therapy (e.g. OPAT)
Temocillin
- As indicated in the guidelines or after discussion with Microbiology consultant
Tigecycline
- Only on advice of Microbiology or ID consultant