First Line

Important: Therapy

Co-amoxiclav 1.2g IV 8 hourly

Notes:

ADD Gentamicin IV (as per online calculator) if systemic infection/sepsis evidence on admission or deterioration

Mild Penicillin Allergy (e.g. rash)

Important: Therapy

Ceftriaxone 2g IV 24 hourly AND Metronidazole 400mg PO 8 hourly

Notes:

ADD Gentamicin IV (as per online calculator) if systemic infection/sepsis evidence on admission or deterioration

Severe Penicillin Allergy (i.e. anaphylaxis, angioedema, urticaria, respiratory distress)

Important: Therapy

Vancomycin IV (as per online calculator) AND Gentamicin IV (as per online calculator) AND Metronidazole 400mg PO 8 hourly 

Notes:

Important: Notes

Incision & Drainage advised - send pus samples to microbiology.

ADD Fluconazole 400mg PO to empirical regime if yeasts reported on microscopy