First Line

Important: Therapy

Flucloxacillin 500mg-1000mg PO 6 hourly

 

If severe infection requiring admission for IV antibiotics:

Flucloxacillin 2g IV 6 hourly

 

Notes:

Second Line

Important: Therapy

Co-amoxiclav 625mg PO 8 hourly

 

If severe infection requiring admission for IV antibiotics:

Co-amoxiclav 1.2g IV 8 hourly

 

Notes:

Penicillin Allergy

Important: Therapy

Clindamycin 600mg PO 8 hourly

 

If severe infection requiring admission for IV antibiotics

Mild penicillin allergy (e.g. rash) - Ceftriaxone 2g IV 12 hourly +/- Metronidazole 400mg PO 8 hourly

 

Severe Penicillin Allergy (i.e. anaphylaxis, angioedema, urticaria, respiratory distress) -

Vancomycin IV (as per online calculator) +/- Metronidazole 400mg PO 8 hourly

 

Notes: