Lower Respiratory Tract Infection in Pregnancy

First Line

Important: Therapy

Amoxicillin 500mg PO 8 hourly

 

If systemic infection/sepsis:

Co-amoxiclav 1.2g IV 8 hourly AND Erythromycin 500mg PO 6 hourly

Notes:

Penicillin Allergy

Important: Therapy

Erythromycin 500mg PO 6 hourly

 

If systemic infection/sepsis:

Ceftriaxone 2g IV 24 hourly AND Erythromycin 500mg PO 6 hourly

Notes:

If history of severe penicillin allergy (i.e. anaphylaxis, angioedema, urticaria, respiratory distress) discuss with microbiologist.

Important: Notes

Treatment duration: 5 days

 

Oral switch guidance

Review culture results first. If no positive microbiology results to guide:

Preferred regime - Co-amoxiclav 625mg PO 8 hourly +/-  Erythromycin 500mg PO 6 hourly

Alternative - Cefuroxime 500mg PO 12 hourly +/- Erythromycin 500mg PO 6 hourly