First Line

Important: Therapy

Gentamicin IV AND Amoxicillin 1g IV 8 hourly AND Metronidazole 500mg IV 8 hourly

Notes:

Penicillin Allergy

Important: Therapy

Vancomycin IV AND Gentamicin IV AND Metronidazole 500mg IV 8 hourly

Notes:

Important: Notes

Treatment duration: 7 days (may be longer if complicated source of infection e.g. abscess or collection)

 

Oral switch guidance

Review culture results first. If no positive microbiology to guide:

Preferred regime - Co-amoxiclav 625mg PO 8 hourly

Alternative - Co-trimoxazole 960mg PO 12 hourly AND Metronidazole 400mg PO 8 hourly