Skin and soft tissue infections
Cellulitis / soft tissue infection
If no features of systemic infection or osteomyelitis and infection is localised, PO can be used
ORAL
FLUCLOXACILLIN 1g QDS
If true penicillin allergy:
CLARITHROMYCIN 500mg BD
If MRSA suspected or known
DOXYCYCYLINE 200mg OD (check isolate is sensitive)
INTRAVENOUS
TEICOPLANIN See separate guidance for 3-times weekly administration
Alternative
CEFTRIAXONE 2g OD (do not use if MRSA suspected or known)
Duration 7 days
Therapeutic drug monitoring of teicoplanin is not required for short courses. If > 7 days treatment planned seek Microbiology advice.
Diabetic foot infectionSee NHS Fife Diabetic Foot Infection guidance