Cellulitis / soft tissue infection

If no features of systemic infection or osteomyelitis and infection is localised, PO can be used

ORAL

FLUCLOXACILLIN 1g QDS

If true penicillin allergy:

CLARITHROMYCIN 500mg BD

If MRSA suspected or known

DOXYCYCYLINE 200mg OD (check isolate is sensitive)

INTRAVENOUS

TEICOPLANIN See separate guidance for 3-times weekly administration

Alternative

CEFTRIAXONE 2g OD (do not use if MRSA suspected or known)

Duration 7 days

Therapeutic drug monitoring of teicoplanin is not required for short courses. If > 7 days treatment planned seek Microbiology advice.

Diabetic foot infectionSee NHS Fife Diabetic Foot Infection guidance