Antimicrobial prescribing: NHS BordersImportant: Therapy
Flucloxacillin IV 2g 6 hourly
+
Ciprofloxacin IV 400mg 12 hourly (IV for 1st dose, then review if appropriate to switch patient to oral).
+
Clindamycin IV 600mg to 1.2g 6 hourly
Necrotising Fasciitis
Important: Therapy
Vancomycin IV (dosing as per guideline. Use vancomycin calculator)
+
Ciprofloxacin IV 400mg 12 hourly (IV for 1st dose, then review if appropriate to switch patient to oral).
+
Clindamycin IV 600mg to 1.2g 6 hourly
Notes:
Important: Notes
Discuss with Consultant Microbiologist.
Fluroquinolones
Refer to important safety information for all quinolones prior to prescribing.
See MHRA Drug Safety Update January 2024: Fluoroquinolones must only be used in situations when other antibiotics, that are commonly recommended for the infection, are inappropriate such as:
- there is resistance to other first-line antibiotics recommended for the infection
- other first-line antibiotics are contraindicated in an individual patient
- other first-line antibiotics have caused side effects in the patient requiring treatment to be stopped
treatment with other first-line antibiotics has failed