Important: Therapy notes
- MHRA advice: Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy (May 2019) (www.gov.uk)
Important: Formulation and dosage details
Formulation:
Injection 50% 1 gram/2mL (Restricted: Hospital use only)
Dosage:
For severe asthma off-label, following consultation with senior medical staff. Magnesium sulfate 1·2 to 2 grams may be given by intravenous infusion over 20 minutes.
Guidance:
- SIGN 158 asthma guidance.
- Asthma in adults (Guidelines)